Postgenome-based Systemic Discovery of Strong Biomarkers Predict Gastric Cancer Chemotherapy Response
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY
* discovery and validation of biomarker predicting gastric cancer chemotherapy response * Analysis for expression level of mRNA using Next generation sequencing in gastric cancer tissue by chemotherapy response * Analysis for expression level of miRNA using Next generation sequencing in gastric cancer tissue and blood by chemotherapy response * Validation of mRNA and miRNA using qRT-PCR in multiple independent cohort * Biological biomarkers-clinical factor combined prediction model of gastric cancer chemotherapy response
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 80
Healthy Volunteers: f
View:
• new gastric cancer patients who has scheduled to start 1st cycle of chemotherapy
• patients who agreed this study and voluntarily assigned the informed consents.
Locations
Other Locations
Republic of Korea
Kyungpook National University Medical Canter
RECRUITING
Daegu
Contact Information
Primary
Su Youn Nam, MD, PhD
nam20131114@gmail.com
82-53-200-2610
Time Frame
Start Date: 2015-11-30
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 800
Treatments
responder in palliative chemotherapy
After initial chemotherapy, responder (complete remission, partial remission)
non-responder in palliative chemotherapy
After initial chemotherapy, disease progression
responder in adjuvant chemotherapy
complete cure and no recurrence at least 1 year after treatment
non-responder in adjuvant chemotherapy
non-complete cure or recurrence within 1 year after treatment
Related Therapeutic Areas
Sponsors
Leads: Kyungpook National University Hospital